Cytochalasins U and V, two new cytochalasans, from var.

Tetrahedron
1992.0

Abstract

Two additional cytochalasins were isolated from liquid culture filtrates of Phoma exiuua var. heteromorvha together with some already known cytochalasins. The two new metabolites, named cytochalasin U and V, represent the first natural occurrence of a 25,26-dioxa(161 and 2% oxa[lS]cytochalasan, respectively, both bearing a formyl group on the macrocyclic ring. Cytochalasins U and V showed respectively significant and weak activity in the brine shrimp assay.

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