Phenopyrrozin, a New Radical Scavenger Produced by Penicillium sp. FO-2047.

The Journal of Antibiotics
1995.0

Abstract

A new radical scavenger, named phenopyrrozin, was isolated from the culture broth of Penicillium sp. FO-2047. Phenopyrrozin was purified from whole broth solvent extraction, silica gel chromatography, and HPLC. The structure of phenopyrrozin was elucidated as 5,6,7,7a-tetrahydro-2-hydroxy-1-phenyl-3H-pyrrolizin-3-one. The IC50 of phenopyrrozin against lipid peroxidation induced by Cr2K2O7 was 73 micrograms/ml. Phenopyrrozin also reduced chromosomal aberrations induced by paraquat.

Knowledge Graph

Similar Paper

Phenopyrrozin, a New Radical Scavenger Produced by Penicillium sp. FO-2047.
The Journal of Antibiotics 1995.0
Phenazoviridin, a novel free radical scavenger from Streptomyces sp. Taxonomy, fermentation, isolation, structure elucidation and biological properties.
The Journal of Antibiotics 1993.0
2,3,4-Trimethyl-5,7-dihydroxy-2,3-dihydrobenzofuran, a Novel Antioxidant, from <i>Penicillium citrinum</i> F5
Journal of Natural Products 2002.0
Isolation and structural elucidation of pyridoxatin, a free radical scavenger of microbial origin.
The Journal of Antibiotics 1991.0
Pyrrolostatin, a novel lipid peroxidation inhibitor from Streptomyces chrestomyceticus. Taxonomy, fermentation, isolation, structure elucidation and biological properties.
The Journal of Antibiotics 1993.0
Penipyrols A–B and peniamidones A–D from the mangrove derived Penicillium solitum GWQ-143
Archives of Pharmacal Research 2015.0
10T024A, a New Phenazine Derivative, as a Radical Scavenger and a Prostaglandin, Leukotriene Release Suppressor
Bioscience, Biotechnology, and Biochemistry 2011.0
Structure of Benthophoenin, a New Free Radical Scavenger Produced by Streptomyces prunicolor
Journal of Natural Products 1993.0
Surugapyrroles A and B, Two New<i>N</i>-Hydroxypyrroles, as DPPH Radical-Scavengers from<i>Streptomyces</i>sp. USF-6280 Strain
Bioscience, Biotechnology, and Biochemistry 2009.0
Surugapyrroles A and B, Two New<i>N</i>-Hydroxypyrroles, as DPPH Radical-Scavengers from<i>Streptomyces</i>sp. USF-6280 Strain
Bioscience, Biotechnology, and Biochemistry 2009.0