Oxysporidinone:  A Novel, Antifungal N-Methyl-4-hydroxy-2-pyridone from Fusarium oxysporum

Journal of Natural Products
1997.0

Abstract

Oxysporidinone (1), a novel 3,5-disubstituted N-methyl-4-hydroxy-2-pyridone, was isolated from fermentations of Fusarium oxysporum (CBS 330.95) by counter-current chromatography. The structure was determined by spectroscopic methods including NMR, MS, IR, and UV analysis. Oxysporidinone exhibited growth inhibitory activity against several common plant pathogenic fungi.

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