A Single-Component Flavoenzyme Catalyzed Regioselective Halogenation of Pyrone in the Biosynthesis of Venemycins

A Single-Component Flavoenzyme Catalyzed Regioselective Halogenation of Pyrone in the Biosynthesis of Venemycins Discovery of Unusual Biaryl Polyketides by Activation of a Silent<i>Streptomyces venezuelae</i>Biosynthetic Gene Cluster The chloroalkaloid (−)-acutumine is biosynthesized via a Fe(II)- and 2-oxoglutarate-dependent halogenase in Menispermaceae plants Recombinant flavin‐dependent halogenases are functional in tobacco chloroplasts without co‐expression of flavin reductase genes Non-geminal Aliphatic Dihalogenation Pattern in Dichlorinated Diaporthins from Hamigera fusca NRRL 35721 Digitalis-like Compounds of Toad Bile: Sulfation and Reduction of Bufadienolides Decrease Potency of Na+, K+- ATPase Inhibition Discovery and characterization of a marine bacterial SAM-dependent chlorinase Expanding the Chemical Diversity of Fasamycin Via Genome Mining and Biocatalysis Unveiling Two Consecutive Hydroxylations: Mechanisms of Aromatic Hydroxylations Catalyzed by Flavin‐Dependent Monooxygenases for the Biosynthesis of Actinorhodin and Related Antibiotics A Regioselective Tryptophan 5-Halogenase Is Involved in Pyrroindomycin Biosynthesis in Streptomyces rugosporus LL-42D005