Isolation and structures of AK-toxin I and II. Host-specific phytotoxic metabolites produced by Alternaria alternata Japanese pear pathotype.

Agricultural and Biological Chemistry
1985.0

Abstract

Two host-specific phytotoxic metabolites, AK-toxin I and II, were isolated from a culture broth of Alternaria alternata Japanese pear pathotype, the fungus causing black spot disease of susceptible Japanese pear cultivars. From chemical, spectral and X-ray crystallographic data, AK- toxin I was characterized as 8-[(2/S, 3/5')-2/-acetylamino-3/-methyl-3/-phenyl-propionyloxy]- (8i?, 95')-9, 10-epoxy-9-methyl-deca-(2JE:, 4Z, 6£)-trienoic acid. The structure of AK-toxin II was also assigned to be 3'-demethyl derivative of AK-toxin I by comparing the spectral data with those of AK-toxinI.

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