Two new pyrroloquinazoline alkaloids, viz. 1,2,3,9-tetrahydropyrrolo(2,1-b)-quinazolin-9-one-3R- hydroxy-3(2'-dimethylamino phenyl (desmethoxyaniflorine) and 7-methoxy-3R-hydroxy-1,2,3,9-tetrahydropyrrolo [2,1-b]-quinazolin-9-one (7-methoxyvasicinone), together with several known compounds were isolated from the leaves of Adhatoda vasica. Their structures were established by spectroscopic and X-ray diffraction analyses.