The 2-methylbutanoate tetraacetate and 2-methylbutanoate pentaacetate derivatives of synadenol, a new lathyrane diterpenoid, have been isolated from Synadenium compacturn N.E. Br. var. compactum (Euphorbiaceae). The structure was elucidated using single crystal X-ray crystallography in conjunction with one and two-dimensional high field NMR experiments and mass spectrometry.