From the stem bark of Erythrina sacleuxii two new iso¯avanones, (R)-5,7-dihydroxy-20 ,40 ,50 -trimethoxyiso¯avanone (trivial name, (R)-2,3-dihydro-7-demethylrobustigenin) and (R)-5-hydroxy-20 ,40 ,50 -trimethoxy-200,200-dimethylpyrano[500,600:6,7]iso¯avanone (trivial name, (R)-saclenone) were isolated. In addition the known compounds shinpterocarpin, 2,3-dehydrokievitone, abyssinone V, abyssinone V-40 -methyl ether, erythrinasinate and 40 -O-methylsigmoidin B were isolated. The structures were determined on the basis of spectroscopic evidence.