Dolastatin 3 and Two Novel Cyclic Peptides from a Palauan Collection of Lyngbya majuscula

Journal of Natural Products
2000.0

Abstract

A collection of Lyngbya majuscula from Palau contained the peptides dolastatin 3 (1), homodolastatin 3 (2), and kororamide (3), together with aplysiatoxin (4), debromoaplysiatoxin (5), and oscillatoxin A (6). The structures of the new peptides homodolastatin 3 (2) and kororamide (3) were determined by interpretation of spectroscopic data and chemical degradation.

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