RA-dimer A, a novel dimeric antitumor bicyclic hexapeptide from Rubia cordifolia L.

Tetrahedron Letters
2000.0

Abstract

A novel antitumor bicyclic hexapeptide dimer, RA-dimer A (3), was isolated from the roots of Rubia cordifolia L. The structure of 3 was determined by analysis of spectroscopic data and chemical correlations. Peptide 3 is the ®rst example of the RA congeners having a dimeric structure.

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