PF1163A and B, New Antifungal Antibiotics Produced by Penicilium sp. II. Physico-chemical Properties and Structure Elucidation.

The Journal of Antibiotics
2000.0

Abstract

The structures of new antifungal antibiotics, PF1163A and B, were elucidated by spectroscopic analyses of the degradation products and by X-ray crystallography of the de-2-hydroxyethyl derivative of PF1163B. Both antibiotics consist of a 13-membered macrocyclic structure containing a derivative of N-methyl tyrosine and a hydroxy fatty acid. PF1163A differs from PF 1163B by having an additional hydroxyl group on the side chain.

DOI： 10.7164/ANTIBIOTICS.53.38

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