Engineering Escherichia coli to improve tryptophan production via genetic manipulation of precursor and cofactor pathways

Synthetic and Systems Biotechnology
2020.0

Abstract

Optimizing the supply of biosynthetic precursors and cofactors is usually an effective metabolic strategy to improve the production of target compounds. Here, the combination of optimizing precursor synthesis and balancing cofactor metabolism was adopted to improve tryptophan production in

Knowledge Graph

Similar Paper

Engineering Escherichia coli to improve tryptophan production via genetic manipulation of precursor and cofactor pathways
Synthetic and Systems Biotechnology 2020.0
Developing E. coli-E. coli co-cultures to overcome barriers of heterologous tryptamine biosynthesis
Metabolic Engineering Communications 2020.0
Optimal cofactor swapping can increase the theoretical yield for chemical production in Escherichia coli and Saccharomyces cerevisiae
Metabolic Engineering 2014.0
Optimal cofactor swapping can increase the theoretical yield for chemical production in Escherichia coli and Saccharomyces cerevisiae
Metabolic Engineering 2014.0
Increased Production of Riboflavin by Coordinated Expression of Multiple Genes in Operons in <i>Bacillus subtilis</i>
ACS Synthetic Biology 2022.0
Experimental and computational optimization of an Escherichia coli co-culture for the efficient production of flavonoids
Metabolic Engineering 2016.0
Metabolic engineering of <i>Corynebacterium glutamicum</i> for improved <scp>l</scp>-arginine synthesis by enhancing NADPH supply
Journal of Industrial Microbiology and Biotechnology 2019.0
Complete Biosynthesis of Anthocyanins Using <i>E. coli</i> Polycultures
mBio 2017.0
Overcoming heterologous protein interdependency to optimize P450-mediated Taxol precursor synthesis in <i>Escherichia coli</i>
Proceedings of the National Academy of Sciences 2016.0
Improvement of Squalene Production from CO<sub>2</sub> in <i>Synechococcus elongatus</i> PCC 7942 by Metabolic Engineering and Scalable Production in a Photobioreactor
ACS Synthetic Biology 2017.0