A new β-carboline alkaloid isolated from the marine sponge Hyrtios erecta

Tetrahedron Letters
1996.0

Abstract

A novel beta-carboline alkaloid, called hyrtiomanzamine, was isolated from the marine sponge Hyrtios erecta collected in the Red Sea Its structure elucidation was carried out by application of various one and two D NMR methods. Hyrtiomanzamine 1 is the first 6-OH-beta-carboline ring associated to a betaine unit isolated from the marine sponge Hyrtios erecta. Hyrtiomanzamine 1 showed immunosuppressive activity in the B lymphocytes reaction assay. Copyright (C) 1996 Elsevier Science Ltd

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