Yangpumicins F and G, Enediyne Congeners from Micromonospora yangpuensis DSM 45577

Journal of Natural Products
2019.0

Abstract

Enediyne natural products are among the most cytotoxic small molecules and thus excellent payload candidates for the development of antibody-drug conjugates (ADCs). Here we report the isolation and structural elucidation of two new 10-membered anthraquinone-fused enediynes, yangpumicins (YPM) F (

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