Halitulin, a new cytotoxic alkaloid from the marine sponge Haliclona tulearensis

Tetrahedron Letters
1999.0

Abstract

Halitulin (2), a novel bisquinolinylpyrrole has been isolated from the sponge Haliclona tulearensis. Its structure was elucidated mainly on the basis of spectroscopic data as well as chemical modifications. Halitulin was found to be cytotoxic against several tumor cells: P-388, A-549, HT-29 and MEL-28 in concentrations of 12-25 ng/ml. (C) 1999 Elsevier Science Ltd. All rights reserved.

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