UK-2A, B, C and D, Novel Antifungal Antibiotics from Streptomyces sp. 517-02. I. Fermentation, Isolation, and Biological Properties.

The Journal of Antibiotics
1996.0

Abstract

Novel antifungal antibiotics, UK-2A, B and a mixture of C and D, were obtained from the mycelial cake of Streptomyces sp. 517-02. All of the UK-2 compounds were similar in structure to antimycin A. The antifungal activities of UK-2 compounds were as strong as that of antimycin A. However, the UK-2 compounds demonstrated weak cytotoxicity compared to antimycin A.

DOI： 10.7164/antibiotics.49.639

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