Botryllamides E−H, Four New Tyrosine Derivatives from the Ascidian Botrylloides tyreum

Journal of Natural Products
2004.0

Abstract

A specimen of the ascidian Botrylloides tyreum from Palau contained the known metabolites botryllamides A (5) and C (7) together with four new tyrosine derivatives, botryllamides E-H (1-4), the structures of which were elucidated by interpretation of spectroscopic data. The botryllamides exhibited weak cytotoxicity against the HCT-116 cell line.

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