<jats:title>Abstract</jats:title><jats:p>A detailed study of the alkaloids from <jats:italic>Tabernaemontana citrifolia</jats:italic>, a species growing in Cuba is presented. Thirteen alkaloids were isolated and characterized. One of these, (−)‐19‐oxovoacristine (<jats:bold>7</jats:bold>), is a new compound isolated for the first lime from a natural source.