An investigation of the natural product chemistry of the red alga Laurencia flexilis, from the Philippines, yielded six known and two new secondary metabolites, the halogenated lipid, (2Z)-2-chloro-pentadec-2-enal, and the chamigrene, (2Z,6S*,9R*)-chamigr-2,5(14)-dien-8-one. The isolation of (2S*,6R*,8R*,9R*)-2,8-dibromo-9-hydroxy-β-chamigrene as a natural product and the unambiguous assignment of its NMR spectral data are reported for the first time.