Sodium 1-(12-Hydroxy)octadecanyl Sulfate, an MMP2 Inhibitor, Isolated from a Tunicate of the Family Polyclinidae

Journal of Natural Products
2002.0

Abstract

Sodium 1-(12-hydroxy)octadecanyl sulfate (1) was isolated from a marine tunicate as a matrix metalloproteinase 2 (MMP2) inhibitor.(1) The structure was elucidated by a combination of spectroscopic and chemical methods. Compound 1 inhibited MMP2 with an IC(50) value of 9.0 microg/mL.

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