Isolation and Structure of the Sex Pheromone Inhibitor, iAM373, ofEnterococcus faecalis

Bioscience, Biotechnology, and Biochemistry
1995.0

Abstract

An Enterococcus faecalis plasmid, pAM373, has a high frequency of transfer in a liquid medium when induced by a recipient-produced sex pheromone, cAM373. The sex pheromone inhibitor against cAM373, termed iAM373, was isolated from a culture supernatant of E. faecalis harboring pAM377 (=pAM373::Tn917), and its structure was identified as a heptapeptide, H-Ser-lle-Phe-Thr-Leu-Val-Ala-OH.

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