From the aerial parts of Bupleurum spinosum, four new natural products have been isolated: (3E, 5Z, 7Z, 9E)-trideca-3, 5, 7, 9-tetraene, 10(14)-trien-1-ol, Z-8-decene-4, 6-diyn-1-ol, (E, E)-pentadeca-5, 7-diene-9,11,13-trivn-2-one, tamarixetin 3-robinobioside. A series of esters of achilleol A with fatty acids has been also found.