Four new triterpenoids; One oleanane-, one ursane- and two cycloartane-type triterpenoids, named amphipaniculosides A-D, in addition to one new aliphatic alcohol glycoside, named amphipaniculoside E, were isolated from the 1-BuOH fraction of the leaves of Amphilophium paniculatum (L.) Kunth., together with five known compounds, (+)-lyoniresinol 3α-O-β-D-glucopyranoside, (-)-lyoniresinol 3α-O-β-D-glucopyranoside, acteoside (verbascoside), isoacteoside (isoverbascoside), and luteolin 7-O-β-D-glucopyranoside. Their structures were elucidated by spectroscopic methods including 1D and 2D NMR experiments ((1)H, (13)C, DEPT, COSY, ROESY, HSQC, HMBC) in combination with HR-ESI-MS and by comparisons of their physical and spectroscopic data with literature values.