<jats:p> Kenyan Croton sylvaticus Hochst. ex Krauss gave four clerodane diterpenoids, the new ent–3,13 E-clerodadiene-15-formate (1), the known 15-acetoxy- ent-3,13 E-clerodadiene (2), ent-3,13 E-clerodadien-15-ol (3) and hardwickiic acid (4), two known halimane diterpenoids, penduliflaworosin (5) and crotohalimaneic acid (6) and one labdane diterpenoid, labda-13 E-ene-8α,15-diol (7). The compounds, when tested for their anti-microbial activities against Bacillus subtilis, Xanthomonas campestris and Candida albicans, were found to be inactive.