Total Synthesis of the Marine Cyclic Depsipeptide Viequeamide A

Journal of Natural Products
2013.0

Abstract

The first total synthesis of viequeamide A, a natural cyclic depsipeptide isolated from a marine button cyanobacterium, was achieved with the N-Me-Val-Thr peptide bond as the final macrocyclization site. The synthetic product gave nearly identical spectroscopic data to that reported for the natural product.

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