Alkaloids of Meconopsis cambrica (L.) VIG. and M. robusta HOOK. f. et THOMS.

Collection of Czechoslovak Chemical Communications
1996.0

Abstract

<jats:p>Additional alkaloids (+)-roemerine (<jats:bold>3b</jats:bold>), (+)-corytuberine (<jats:bold>3d</jats:bold>), (-)-<jats:italic>N</jats:italic>-methylmecambridinium and alkaloid MC 2 (the last two as iodides) were isolated as minor alkaloidal components from <jats:italic>Meconopsis cambrica</jats:italic> (L.) VIG. (<jats:italic>Papaveraceae</jats:italic>) besides of the dominant known alkaloids (-)-mecambrine (<jats:bold>1</jats:bold>), (-)-mecambridine (<jats:bold>2</jats:bold>), (-)-flavinantine (<jats:bold>4</jats:bold>) and (+)-magnoflorine (<jats:bold>5</jats:bold>), and a small amount of (+)-mecambroline (<jats:bold>3a</jats:bold>). Minute quantities of protopine, allocryptopine, roemeroline, papaverrubine D and C, berberine, coptisine, corysamine and palmatine were identified by thin layer chromatography (TLC). From <jats:italic>M. robusta</jats:italic> HOOK. f. et THOMS., protopine, (-)-amurensinine (<jats:bold>6</jats:bold>) and two incompletely characterized alkaloids MRO 1 and MRO 2 were isolated, and allocryptopine, cryptopine, rhoeadine, 6-methoxy-2-methyl-1,2,3,4-tetrahydro-β-carboline, alkaloid MR 1, coptisine, corysamine, magnoflorine, corytuberine and <jats:italic>N</jats:italic>-methylamurensininium salt were detected on TLC.

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