Saroclazines A–C, thio-diketopiperazines from mangrove-derived fungi Sarocladium kiliense HDN11-84

Archives of Pharmacal Research
2018.0

Abstract

Three new diketopiperazine derivatives (DKPs), saroclazines A-C (1-3) along with three known DKPs (4-6) were isolated from mangrove-derived fungi Sarocladium kiliense HDN11-84. Saroclazines A-B (1 and 2) possessed a free amide structure, which was first found in sulfur-containing aromatic DKPs. Their structures were elucidated by NMR, HRESIMS and X-ray. The cytotoxic activity of new compounds (1-3) was tested against HeLa cell lines, among which compound 2 showed an IC

Knowledge Graph

Similar Paper

Saroclazines A–C, thio-diketopiperazines from mangrove-derived fungi Sarocladium kiliense HDN11-84
Archives of Pharmacal Research 2018.0
Saroclides A and B, Cyclic Depsipeptides from the Mangrove-Derived Fungus <i>Sarocladium kiliense</i> HDN11-112
Journal of Natural Products 2018.0
Saroclides A and B, Cyclic Depsipeptides from the Mangrove-Derived Fungus Sarocladium kiliense HDN11-112
Journal of Natural Products 2018.0
A new diketopiperazine derivative from a deep sea-derived <i>Streptomyces</i> sp. SCSIO 04496
Natural Product Research 2016.0
Three Diketopiperazine Alkaloids with Spirocyclic Skeletons and One Bisthiodiketopiperazine Derivative from the Mangrove-Derived Endophytic Fungus <i>Penicillium brocae</i> MA-231
Organic Letters 2016.0
Brocazines A–F, Cytotoxic Bisthiodiketopiperazine Derivatives from <i>Penicillium brocae</i> MA-231, an Endophytic Fungus Derived from the Marine Mangrove Plant <i>Avicennia marina</i>
Journal of Natural Products 2014.0
Brocazines A–F, Cytotoxic Bisthiodiketopiperazine Derivatives from <i>Penicillium brocae</i> MA-231, an Endophytic Fungus Derived from the Marine Mangrove Plant <i>Avicennia marina</i>
Journal of Natural Products 2014.0
Thiodiketopiperazines from the Marine-Derived Fungus <i>Phoma</i> sp. OUCMDZ-1847
Journal of Natural Products 2014.0
Thiodiketopiperazines from the Marine-Derived Fungus <i>Phoma</i> sp. OUCMDZ-1847
Journal of Natural Products 2014.0
2,5-Diketopiperazines From a Sponge-Derived Fungus Aspergillus sclerotiorum
Frontiers in Microbiology 2022.0