Petsidine fromKorolkowia sewerzowii

Chemistry of Natural Compounds
1985.0

Abstract

Continuing an investigation of the epigeal part of Korolkowia sewerzowii Regel., the methanol mother solution from korseveriline and the acetone mother solution from korseveridine [1] were chromatographed separately on a column of alumina. Elution with chloroform-methanol (10:0.5) gave a base (II) with mp 150-152°C (acetone), [α]D -13° (c 0.7; chloroform), M+ 427. When (II) was acetylated with acetic anhydride in pyridine, a O,N-diacetyl derivative (IV) was obtained with M+ 511. A comparison of the physical constant and spectral characteristics of alkaloid (II) and of an authentic sample of petisidine [3-7] showed their identity (melting point of a mixture, Rf values, and IR, PMR, and mass spectra). This is the first time that petisidine has been detected in plants from the genus Korolkowia.

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