Production of N-acetylisopenicillin N and isopenicillin N from Streptomyces tokunoensis sp. nov.

The Journal of Antibiotics
1982.0

Abstract

N-Acetylisopenicillin N was isolated from the culture broth of Streptomyces tokunonensis sp. nov., and identified from 1H NMR spectroscopy and release of L-alpha-aminoadipic acid by acid hydrolysis. In the course of this study, the specimen of penicillin N isolated from this strain was proved to contain a small amount of isopenicillin N by HPLC.

DOI： 10.7164/ANTIBIOTICS.35.1646

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