Six new alkaloids, periphylline 1, isoperiphylline 5, dihydroperiphylline 21, neoperiphylline 22, perimargine 23 and dihydroperimargine 24 have been isolated from the leaves of Peripterygia marginata. All these alkaloids contain a thirteen-membered ring system derived from dicinnamoylspermidine. © 1977.