Discovery and characterisation of an amidine-containing ribosomally-synthesised peptide that is widely distributed in nature

Chemical Science
2021.0

Abstract

<jats:p>Genome mining for pathways containing YcaO proteins revealed a widespread novel family of RiPP gene clusters. A model gene cluster was characterised through genetic and chemical analyses, which yielded streptamidine, a novel amidine-containing RiPP.

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