Literature

Abstract

A new microbial metabolite Sch 725424 (1) was isolated from the culture of Kitasatospora sp. The structure elucidation of 1 was accomplished based on NMR spectroscopic analyses as well as extensive structure elucidation of its dehydration product Sch 725428 (2). Compound 1 showed inhibitory activity against Staphylococcus aureus with MIC values 1-2 microg/ml, and also displayed weak antifungal activity against Saccharomyces cerevisiae (PM503) with an MIC 32 microg/ml.

DOI： 10.1038/JA.2005.22

New Antibiotic Sch 725424 and Its Dehydration Product Sch 725428 from Kitasatospora sp.

The Journal of Antibiotics 2005.0

A Novel Macrolactam-trisaccharide Antifungal Antibiotic. Taxonomy, Fermentation, Isolation, Physico-chemical Properties, Structure Elucidation and Biological Activity.

The Journal of Antibiotics 1998.0

Sch 37137, a novel antifungal compound produced by a Micromonospora sp. Taxonomy, fermentation, isolation, structure and biological properties.

The Journal of Antibiotics 1988.0

A New Bicyclic Guanidine Alkaloid, Sch 575948, from a Marine Sponge, Ptilocaulis spiculifer

The Journal of Antibiotics 2003.0

A novel macrolactam-disaccharide antifungal antibiotic. Taxonomy, fermentation, isolation, physico-chemical properties, structure elucidation and biological activity.

The Journal of Antibiotics 1993.0

SCH 42137, a novel antifungal antibiotic from an Actinoplanes sp. Fermentation, isolation, structure and biological properties.