Nostocyclin, a novel 3-amino-6-hydroxy-2-piperidone-containing cyclic depsipeptide from the cyanobacterium Nostoc sp.

Tetrahedron Letters
1996.0

Abstract

Nostocyclin, a novel 3-amino-6-hydroxy-2-piperidone-containing cyclic peptide was isolated from a hepatotoxic strain of cyanobacterium Nostoc sp. Nostocyclin is non-toxic in acute in vivo bioassays, but inhibits protein phosphatase-1 activity at high concentration in vitro.

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