Search for antimycobacterial constituents from a Tibetan medicinal plant, Gentianopsis paludosa

Abstract

<jats:title>Abstract</jats:title><jats:p>From the whole plant of <jats:italic>Gentianopsis paludosa</jats:italic> seven compounds were isolated and identified to be 1,7‐dihydroxy‐3,8‐dimethoxyxanthone (1), 1,7,8‐trihydroxy‐3‐methoxyxanthone (2), 1‐hydroxy‐3,7,8‐trimethoxyxanthone (3), 1,8‐dihydroxy‐2,6‐dimethoxyxanthone (4), oleanolic acid (5), 4′,5,7‐trihydroxyflavone (6) and luteolin‐7‐O‐glucoside (7). Compounds 1, 2, 3 and 5 showed modest inhibitory effect against the growth of <jats:italic>Mycobacterium smegmatis</jats:italic> and <jats:italic>M. tuberculosis</jats:italic>. Copyright © 2008 John Wiley &amp; Sons, Ltd.