Anti-influenza activities of polyphenols from the medicinal mushroom Phellinus baumii

Bioorganic & Medicinal Chemistry Letters
2015.0

Abstract

Five polyphenols were isolated from the ethanolic extract of the fruiting bodies of Phellinus baumii. These compounds were identified by various spectroscopic methods as hispidin, hypholomine B, inoscavin A, davallialactone, and phelligridin D. All compounds inhibited noncompetitively H1N1, H5N1, and H3N2 neuraminidase activity and reduced the amount of virally-induced cytopathic effect (CPE) according to an MDCK cell-based assay.

Knowledge Graph

Similar Paper

Anti-influenza activities of polyphenols from the medicinal mushroom Phellinus baumii
Bioorganic & Medicinal Chemistry Letters 2015.0
Phenolic compounds with NF-κB inhibitory effects from the fungus Phellinus baumii
Bioorganic & Medicinal Chemistry Letters 2011.0
Styrylpyrones from the medicinal fungus Phellinus baumii and their antioxidant properties
Bioorganic & Medicinal Chemistry Letters 2010.0
Pyronepolyene C-glucosides with NF-κB inhibitory and anti-influenza A viral (H1N1) activities from the sponge-associated fungus Epicoccum sp. JJY40
Bioorganic & Medicinal Chemistry Letters 2012.0
Inhibition of neuraminidase activity by polyphenol compounds isolated from the roots of Glycyrrhiza uralensis
Bioorganic & Medicinal Chemistry Letters 2010.0
<i>C</i>-Methylated Flavonoid Glycosides from <i>Pentarhizidium orientale</i> Rhizomes and Their Inhibitory Effects on the H1N1 Influenza Virus
Journal of Natural Products 2017.0
Neuraminidase inhibitory activities of flavonols isolated from Rhodiola rosea roots and their in vitro anti-influenza viral activities
Bioorganic &amp; Medicinal Chemistry 2009.0
Xanthones from Polygala karensium inhibit neuraminidases from influenza A viruses
Bioorganic &amp; Medicinal Chemistry Letters 2012.0
Aspulvinones from a mangrove rhizosphere soil-derived fungus Aspergillus terreus Gwq-48 with anti-influenza A viral (H1N1) activity
Bioorganic &amp; Medicinal Chemistry Letters 2013.0
Design, synthesis and biological evaluation of small molecular polyphenols as entry inhibitors against H5N1
Bioorganic &amp; Medicinal Chemistry Letters 2014.0