Labdane Diterpenoid Glycosides from Alpinia densespicata and Their Nitric Oxide Inhibitory Activities in Macrophages

Journal of Natural Products
2009.0

Abstract

Four new labdane diterpene glycosides (1-4) named alpindenosides A, B, C, and D, two new norditerpene glycosides (5, 6) named noralpindenosides A and B, and three known flavonoid glycosides (7-9) have been isolated from the stems of Alpinia densespicata. Structural elucidation of compounds 1-6 was based on spectroscopic data. Compounds 1-9 all exhibited moderate NO inhibitory activities, whereas they were noncytotoxic at 20 microM against several human tumor cell lines.

Knowledge Graph

Similar Paper

Labdane Diterpenoid Glycosides from <i>Alpinia densespicata</i> and Their Nitric Oxide Inhibitory Activities in Macrophages
Journal of Natural Products 2009.0
Inhibitory activity of eudesmane sesquiterpenes from Alpinia oxyphylla on production of nitric oxide
Bioorganic &amp; Medicinal Chemistry Letters 2012.0
New eudesmane sesquiterpenes from Alpinia oxyphylla and determination of their inhibitory effects on microglia
Bioorganic &amp; Medicinal Chemistry Letters 2013.0
Cytotoxic labdane-type diterpenes from Hedychium longipetalum inhibiting production of nitric oxide
Bioorganic &amp; Medicinal Chemistry Letters 2015.0
Absolute stereostructures of novel norcadinane- and trinoreudesmane-type sesquiterpenes with nitric oxide production inhibitory activity from Alpinia oxyphylla
Bioorganic &amp; Medicinal Chemistry Letters 2001.0
New Labdane diterpenes as intestinal α-glucosidase inhibitor from antihyperglycemic extract of Hedychium spicatum (Ham. Ex Smith) rhizomes
Bioorganic &amp; Medicinal Chemistry Letters 2009.0
Antineurodegenerative Labdane Diterpenoid Glycosides from the Twigs of <i>Pinus koraiensis</i>
Journal of Natural Products 2020.0
Indole alkaloid glycosides from Isatis tinctoria roots
Natural Product Research 2021.0
Anti-inflammatory and α-Glucosidase Inhibitory Activities of Labdane and Norlabdane Diterpenoids from the Rhizomes of <i>Amomum villosum</i>
Journal of Natural Products 2019.0
Anti-inflammatory Labdane Diterpenoids from <i>Lagopsis supina</i>
Journal of Natural Products 2014.0