Cytotoxic, Antitopoisomerase IIα, and Anti-HIV-1 Activities of Triterpenoids Isolated from Leaves and Twigs of Gardenia carinata

Journal of Natural Products
2013.0

Abstract

Eight new cycloartane triterpenoids (1-8), named carinatins A-H, and the known compounds secaubryolide (9) and dikamaliartane D (10) were isolated from the leaves and twigs of Gardenia carinata. Their structures were determined on the basis of spectroscopic methods. Cytotoxic, antitopoisomerase IIα, and anti-HIV-1 activities of compounds 1-7, 9, and 10 were investigated.

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