Daphniphyllum alkaloids are a group of highly complex polycyclic alkaloids which have attracted great interest from a biogenetic point of view.1,2 Heathcock and coworkers have demonstrated a one-pot synthesis of a dialdehyde to a pentacyclic unsaturated amine, which turned out to be an exceptionally efficient way to construct the pentacyclic nucleus of the Daphniphyllum alkaloids, based on the hypothesis of their biosynthesis.3 Recently we have isolated daphnezomines A and B,4 which are novel alkaloids with a unique aza-adamantane core, and daphnezomines C, D, and E,5 with an N-oxide moiety, from the leaves or stems of Daphniphyllum humile, respectively. A further search for biogenetically interesting alkaloids from the same plant resulted in the isolation of daphnezomines F (1) and G (2). Two novel alkaloids obtained from the stems possessed the 1-azabicyclo[5.2.2]undecane ring system. In this paper we describe the isolation and structure elucidation of 1 and 2.