Neolamarckines A and B, New Indole Alkaloids from <i>Neolamarckia cadamba</i>

CHEMICAL &amp; PHARMACEUTICAL BULLETIN
2011.0

Abstract

Two new indole alkaloids, neolamarckines A and B (1, 2) were isolated from the leaves of Neolamarckia cadamba (Rubiaceae). Structural elucidation of 1 and 2 was performed by combination of 2D-NMR and circular dichroism (CD) spectra, and chemical correlations. Neolamarckine A (1) showed inhibition of inducible nitric oxide synthase (iNOS) dose dependently.

DOI： 10.1248/CPB.59.291

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