Botcinins A, B, C, and D, Metabolites Produced by Botrytis cinerea, and Their Antifungal Activity against Magnaporthe grisea, a Pathogen of Rice Blast Disease

Journal of Natural Products
2005.0

Abstract

Four new metabolites, botcinins A-D, were isolated from the culture filtrate of a strain of Botrytis cinerea. Their structures were determined by spectroscopic methods, mainly NMR techniques, molecular modeling, and the modified Mosher's method. They exhibited antifungal activities against Magnaporthegrisea, a pathogen of rice blast disease. Botcinins B and C have a MIC of 12.5 microM, and botcinins A and D are not active below 100 microM.

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