New bisabolane sesquiterpene 9 and sesquiterpenes 8 and 10 along with the known (+)-curcuphenol 1 and (+)-dehydrocurcuphenol 6 were isolated from the n-hexane extract of the sponge Myrmekioderma collected along the Vanuatu coast. Their structures were unambiguously characterized using spectroscopic methods. Two new Myrmekiodermin glycolipid ethers A 11 and B 13 were also isolated from the n-BuOH extract and fully identified.