Six New Constituents from an Ascomycete, Chaetomium quadrangulatum, Found in a Screening Study Focused on Monoamine Oxidase Inhibitory Activity.

Chemical and Pharmaceutical Bulletin
2003.0

Abstract

A screening study focusing on monoamine oxidase inhibitory activity on the EtOAc extract of an Ascomycete Chaetomium quadrangulatum, which previously gave five unique chromones possessing this activity (chaetoquadrins A-E (1-5)), this time afforded six new constituents termed chaetoquadrins F-K (6-11) in addition to 1-5. The structures of 6-11 have been deduced on the basis of spectral and chemical data, and 7 and 8 have shown appreciable monoamine oxidase inhibitory activity.

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