Two new isoflavones, erysenegalensein L, 5,6',4'-trihydroxy-8-(2'''-hydroxy-3'''-methylbut-3'''-enyl)-2 '',2 ''-dimethylpyrano [5 '',6 '',6,7] isoflavone and erysenegalensein M, 5,4'-dihydroxy-8-(2'''-hydroxy-3'''-methylbut-3'''-enyl)-2 '',2 ''-dimethylpyrano [5 '', 6 '': 6, 7] isoflavone have been isolated from the stem bark of the Cameroonian medicinal plant Erythrina senegalensis. The seeds of this plant afforded erysodine, glucoerysodine and, hypaphorine. Their structures were determined by the usual spectroscopic methods, 2D NMR techniques and were confirmed by chemical reactions.