Aspergilazine A, a diketopiperazine dimer with a rare N-1 to C-6 linkage, from a marine-derived fungus Aspergillus taichungensis

Tetrahedron Letters
2012.0

Abstract

A novel diketopiperazine (DKP) dimer, aspergilazine A (1), dimerized by two DKP units via a rare N-1 to C-6 linkage, was isolated from the marine-derived fungus Aspergillus taichungensis ZHN-7-07. The structure was determined by the combination of spectroscopic and Marfey's methods. Biological evaluation indicated that aspergilazine A (1) had a weak activity against influenza A (H1N1) virus.

Knowledge Graph

Similar Paper