Eremophilane‐Type Sesquiterpenoids from the Fermentation Broth of Plant Endophytic Fungus Pestalotiopsis photiniae Isolated from the Chinese Podocarpaceae Plant Podocarpus macrophyllus

Abstract

<jats:title>Abstract</jats:title><jats:p>Two new sesquiterpenoid esters, pestalotiopins B and C (<jats:bold>1</jats:bold> and <jats:bold>2</jats:bold>, resp.) related to the eremophilane class, together with one known compound, berkleasmin C (<jats:bold>3</jats:bold>), were isolated from the fermentation broth of the plant endophytic fungus <jats:italic>Pestalotiopsis photiniae.</jats:italic> Their structures and relative configurations were elucidated by extensive spectroscopic analysis including 1D‐ and 2D‐NMR (HSQC, HMBC, and NOESY), and MS experiments. Compound <jats:bold>1</jats:bold> has an interesting lactam structure, and this type of sesquiterpenoid with a lactam structure is reported for the first time.