The cytotoxic drimane derivatives cinnamodial (1), capsicodendrin (2), a partially characterized tetramer of 1, and cinnamosmolide (3) were obtained from Capsicodendron dinisii (Canellaceae). A new compound, 6 beta-acetoxyisodrimenin (4) and ugandensolide (5) and futronolide (6) were also isolated, but were not cytotoxic.