The isolation and structure elucidation of 15 alkamides from the roots of Echinacea angustifolia is reported. In addition to several compounds previously found in E. purpurea the new undeca-2Z-en-8,10-diynoic acid isobutylamide, dodeca-25en-8,10-diynoic acid isobutylamide, undeca-2Z-en-8,10-diynoic acid 2_methylbutylamide, dodeca-2E-en-8,10-diynoic acid 2_methylbutylamide, hexadeca-2E,9Z-dien-12,14-diynoic acid isobutylamide and dodeca-2E,4Z,lOZ-trien-8-ynoic acid isobutylamide were isolated. The isobutylamide of undeca-25en-8,10-diynoic acid was found for the first time in Echinacea species. All structures were established by UV, IR, NMR and mass spectroscopy.