Clitidine, a new toxic pyridine nucleoside from clitocybe acromelalga

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1982.0

Abstract

From a poisonous mushroom, Clitocybe acromelalga, a new nucleoside clitidine (1) was isolated as a toxic principle. The structure was deduced to be 1 from spectral data and chemical degradation studies. Synthesis of 1 through condensation of methyl Caminonicotinate with 3, 5-di-0-benzoyl-D-ribofuranosyl chloride confirmed the structure, including absolute contiguration.

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