(±)-N-Benzoyl[2-hydroxy-2-(4'-methoxyphenyl)]ethylamine from Clausena brevistyla Oliver (family Rutaceae)

Australian Journal of Chemistry
1967.0

Abstract

Extracts of leaves and branchlets of Clausena brevistyla Oliver, a shrub of the family Rutaceae, did not yield significant amounts of basic alkaloids, but a neutral amide, C₁₈H₁₇NO₃, has been isolated and shown to be (±)-N-benzoyl[2-hydroxy-2-(4'-methoxyphenyl)]ethylamine (I). Amides of this type have been found previously in other rutaceous species, and there is a close relationship between the amide (I) from C. brevistyla and the amides aegelin (II) from Aegle marmelos, herclavin (III) from Zanthoxylum clava-herculis, and N-benzoyltyramine edulis (IV) from Casimiroa.

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