Identification de xanthones et de nouveaux arabinosides de C‐glucosides flavoniques dans Swertia perennisL.

Helvetica Chimica Acta
1976.0

Abstract

<jats:p><jats:italic>Identification of xanthones and new arabinosides of flavone C‐glucosides from</jats:italic> Swertia perennis <jats:sc>L.</jats:sc> – Seven tetraoxygenated xanthones [1,3,7,8‐tetrahydroxy‐xanthone (<jats:bold>1</jats:bold>); 1,8‐dihydroxy‐3,7‐dimethoxy‐xanthone (<jats:bold>2</jats:bold>); 1,7‐dihydroxy‐3,8‐dimethoxy‐xanthone (<jats:bold>3</jats:bold>); 1‐hydroxy‐3,7,8‐trimethoxy‐xanthone (<jats:bold>4</jats:bold>); 3,7,8‐trihydroxy‐xanthone‐xanthone‐1‐0‐β‐glucoside (<jats:bold>5</jats:bold>); 3,7,8‐trimethoxy‐xanthone‐1‐0‐primeveroside (<jats:bold>6</jats:bold>); 8‐hydroxy‐3,7‐dimethoxy‐xanthone‐1‐0‐primeveroside (<jats:bold>7</jats:bold>)] have been isolated chromatographically, using polyamide columns, from roots of <jats:italic>Swertia perennis</jats:italic> <jats:sc>L</jats:sc>. From leaves and stems of the same plant, six xanthones [1,5,8‐trihydroxy‐3‐methoxy‐xanthone (<jats:bold>8</jats:bold>); 1,5‐dihydroxy‐3‐methoxy‐xanthone‐8‐0‐β‐glucoside (<jats:bold>9</jats:bold>); mangiferin (<jats:bold>10</jats:bold>); <jats:bold>1</jats:bold>; <jats:bold>4</jats:bold>; <jats:bold>5</jats:bold>] and four flavone C‐glycosides [iso‐orientin (<jats:bold>11</jats:bold>); isovitexin (<jats:bold>12</jats:bold>); iso‐orientin‐6″‐arabinoside (<jats:bold>13</jats:bold>); isovitexin‐6″‐arabinoside (<jats:bold>14</jats:bold>)] have also been isolated. Among these compounds, <jats:bold>7</jats:bold>, <jats:bold>13</jats:bold> and <jats:bold>14</jats:bold> were not encountered before in nature. In the last two compounds, the position of arabinose on the C‐glucoside moiety of the flavone was established by <jats:sup>13</jats:sup>C‐NMR. spectroscopy.

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